Studies on Sulfonamides. II
نویسندگان
چکیده
منابع مشابه
Studies on Highly Soluble Azo Sulfonamides.
Since the early observations of Kellner (1936) and Fuller (1937), who demonstrated that p-aminobenzenesulfonamide (sulfanilamide) is formed in animal tissues when prontosill or prontosil soluble2 (neoprontosil3) is administered by mouth, and the studies by Domagk (1935), Colebrook and Kenney (1936), and Colebrook, Buttle, and O'Meara (1936), wherein they were unable to demonstrate an antibacter...
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We report the synthesis and characterization of the pyrrole sulfonamide as a new class of potential molecular receptors, including conformational analysis and molecular recognition studies for four pyrrole sulfonamide derivatives.
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Studies previously reported on the mode of action of sulfonamides on bacteria showed that the inhibition of respiratory enzymes of the bacteria caused a proportional inhibition of the growth of Streptococcus pyogenes and pneumococcus, type I. This conclusion was based on simultaneous measurements, at various time intervals, of the increase in the number of bacteria (and the mg of bacterial nitr...
متن کاملStudies on the Action of Sulfonamides on the Respira- Tion and Growth of Bacteria1 A. Factors Controlling the Inhibition by Sulfonamides of Carboxy-
In two previous reports, it was shown that cocarboxylase and p-aminobenzoic acid counteract the inhibitory effect of sulfathiazole on yeast and bacterial carboxylases. Whereas cocarboxylase brings about this effect without exercising any inhibitory action on carboxylase, p-aminobenzoic acid exercises the antagonistic action to sulfathiazole while maintaining a certain degree of inhibitory effec...
متن کاملAssessing antibiotic sorption in soil: a literature review and new case studies on sulfonamides and macrolides
The increased use of veterinary antibiotics in modern agriculture for therapeutic uses and growth promotion has raised concern regarding the environmental impacts of antibiotic residues in soil and water. The mobility and transport of antibiotics in the environment depends on their sorption behavior, which is typically predicted by extrapolating from an experimentally determined soil-water dist...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1964
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.84.6_498